| The Diamond Player of the Year | Shohei Ohtani | Starting Pitcher/ Designated Hitter | Los Angeles Angels |
| Best Starting Pitcher | Max Scherzer | Washington Nationals/ Los Angeles Dodgers |
| Best Relief/Closing Pitcher | Josh Hader | Milwaukee Brewers |
| Best First Baseman | Vladimir Guerrero Jr. | Toronto Blue Jays |
| Best Second Baseman | Marcus Semien | Toronto Blue Jays |
| Best Shortstop | Fernando Tatís Jr. | San Diego Padres |
| Best Third Baseman | Austin Riley | Atlanta Braves |
| Best Right Fielder | Bryce Harper | Philadelphia Phillies |
| Best Center Fielder | Cedrick Mullins | Baltimore Orioles |
| Best Left Fielder | Tyler O’Neill | St. Louis Cardinals |
| Best Designated Hitter | Shohei Ohtani | Los Angeles Angels |
| Best Team | San Francisco Giants | 109-58 |
| Rookie of the Year | Jonathan India | Second Baseman | Cincinnati Reds |
| Comeback Player of the Year | Trey Mancini | First Baseman/ Designated Hitter | Baltimore Orioles |
| Most Improved Player | Cedrick Mullins | Center Fielder | Baltimore Orioles |
| Best Game | New York Yankees @ Chicago White Sox | Field of Dreams Game Aug. 12, 2021 | White Sox: 9 Yankees: 8 |
| Best Pitching Staff | Los Angeles Dodgers |
*Denotes Unanimous Selection